📍 250 Stockport Road, Timperley, Altrincham
Altrincham Travel Clinic

Okavango, Chobe & Kalahari

Botswana travel vaccines and malaria advice

Poling through the Okavango in a mokoro, sleeping under canvas in Moremi or Chobe, driving the Kalahari pans: this is what UK travellers are usually advised before Botswana, and how the month you travel changes the malaria answer.

Hepatitis A & Typhoid
Malaria: Oct to May in the north
Rabies for remote camps
Yellow fever certificate rule
Okavango Delta safari scenery in Botswana

The short answer

Which vaccines and malaria tablets do I need for Botswana?

For most UK visitors to Botswana the list is short: Hepatitis A, Typhoid, and a combined Tetanus, Diphtheria and Polio booster if you're not up to date. What changes from one traveller to the next is malaria. TravelHealthPro classes the northern half of the country, the Okavango Delta included, as high risk from October to May, so antimalarial tablets are advised for a wet-season Delta or Chobe trip. From June to September those areas drop to low risk, and the southern half, Gaborone included, is very low risk all year, where bite avoidance is the advice rather than tablets.

Botswana's safari style shapes the rest. Camps are small, far apart and often reached by light aircraft, so the nearest clinic able to treat a bite properly may be a day away, which is why rabies vaccination moves up the list for wild camping in Moremi, walking safaris or a fortnight or more in the bush. Add the Delta's fresh water, serious heat before the rains and biting insects that are busy by day as well as after dark, and it's a trip that rewards a proper conversation. This guide follows current TravelHealthPro and NHS advice; our pharmacists at 250 Stockport Road in Timperley confirm your own list at a consultation.

Timing

Rabies needs four weeks; a certificate needs ten days

If rabies is on your list, that sets the clock: the standard course is three injections over 28 days, so see us five to six weeks before you fly and everything else, including starting antimalarial tablets before departure, fits around it. Compressed schedules over 21 or 7 days exist if you've left it late; the shortest needs a booster a year on for future trips.

Arriving from a yellow fever country, say after a Kenyan safari? The certificate only becomes valid ten days after the injection, so sort it before the first flight. Leaving from Manchester, Botswana itself asks for nothing, but the rule counts transit as well as arrival and there is no minimum stopover time, so check your connection with us: changing planes in Johannesburg or Dubai is fine, changing in Nairobi or Addis Ababa is not.

Your likely list

Which vaccinations does TravelHealthPro recommend for Botswana?

The first group covers nearly every Botswana itinerary; the second depends on how remote you're going and for how long. Your personal list is confirmed at consultation, and the recommendations mirror TravelHealthPro's current Botswana advice.

Entry rules — separate from your jabs

Yellow fever certificate: what Botswana requires

A yellow fever certificate requirement is a legal condition of entry — it is not the same thing as the vaccine being recommended for your health. The recommendation (when there is one) appears in the vaccine list above; the entry rule is below.

Flying direct from the UK? No yellow fever certificate needed for Botswana

Botswana only asks for a certificate (ICVP) from travellers aged 1 year+ who arrive from — or pass through — a country with yellow fever risk, and any airport layover in a risk country counts, however short. That catches out multi-country itineraries, so check your whole route, not just your destination.

There is no yellow fever transmission risk in Botswana itself — this rule exists purely to stop the virus being carried in from elsewhere.

Malaria, month by month

When do I need malaria tablets for the Okavango Delta and Chobe?

This is the biggest variable on a Botswana trip. TravelHealthPro puts the northern half of the country, taking in the Okavango Delta, Moremi and Chobe, at high risk from October to May, with antimalarial tablets recommended. From June to September the same areas drop to low risk and the advice becomes awareness plus rigorous bite avoidance. The southern half, including Gaborone and the Kgalagadi, is very low risk all year; the Central Kalahari straddles the middle, so for camps there we check the exact location and month. There is no travel vaccine for malaria: it's tablets started before you go and continued after you return, plus repellent, cover-up and nets, with the choice of tablet settled at consultation.

  • Okavango, Moremi and Chobe, October to May: antimalarial tablets recommended
  • Same areas June to September: low risk, so bite avoidance rather than tablets
  • Gaborone, the Kgalagadi and the south: very low risk all year
  • Fever during the trip or within 12 months of getting home: same-day medical advice, and say you have been to a malaria area
Antimalarial tablets explained
Mosquito-bite protection for a wet-season Okavango trip

Remote camps and rabies

Why does rabies matter more in Botswana than on a lodge-based safari?

Rabies is reported in domestic animals in Botswana, and the bigger issue is distance. If a camp dog, a vervet monkey or a bat scratches you at a fly-in camp or on a wild-camping night in Moremi, the treatment you need is urgent, a bush camp won't stock it, and reaching it can mean a charter flight to Maun. Having the full course before you leave doesn't remove the need for urgent treatment after a bite, but it simplifies what's required and buys time. We'd suggest it for wild camping, walking safaris, overnight mokoro trails and any trip of a month or more.

  • Rabies is reported in domestic animals in Botswana
  • Pre-travel course: three injections over 28 days, faster schedules if time is short
  • Any bite, scratch or lick on broken skin still needs urgent medical help, vaccinated or not
Rabies vaccine for safari travellers
Travel health consultation at our Timperley pharmacy

Water, heat and biting insects

What else should I plan for in the Delta and the Kalahari?

Three things catch people out that no vaccine covers. Water: the Okavango is fresh water and TravelHealthPro confirms schistosomiasis (bilharzia) risk in Botswana, so enjoy the mokoro but keep hands and feet inside and don't swim, paddle or wash in the channels. Heat: the dry months before the rains are fierce, and the NHS notes that older people and anyone with a long-term condition such as heart disease or diabetes are more prone to heat exhaustion, so plan shade, rehydration salts and more water than feels natural. Insects: TravelHealthPro lists biting insects and ticks among Botswana's risks, and chikungunya is spread by mosquitoes that bite mainly during daylight hours, so repellent is a daytime job as well as an evening one. Cover up in the bush and use 50% DEET on exposed skin. Ask us about tsetse flies, which bite by day in rural woodland and savannah across Southern Africa and carry sleeping sickness; there is no vaccine for it, so bite cover is the whole defence.

  • Fresh water in the Delta carries bilharzia risk: look, don't swim
  • Heat exhaustion is more likely for children, older travellers and long-term conditions
  • Biting insects are a daytime risk too: chikungunya-carrying mosquitoes bite mainly by day, so wear repellent from morning onwards
Bite avoidance that actually works
Okavango Delta channels and reed beds in Botswana

FAQ

Botswana safari health questions we're asked most

Medically reviewed by Muhammad Adnan, Superintendent Pharmacist (GPhC reg. 2073652) · Last reviewed 2026-09-16
Sources:TravelHealthPro — Botswana country information·NHS — Malaria: prevention and symptoms·NHS — Rabies vaccination for travel·NHS — Yellow fever vaccination and certificatesExternal links open in a new tab. Public-health guidance is reproduced under the Open Government Licence where applicable.

Planning Botswana from South Manchester?

Bring your itinerary, dates and a list of regular medicines to 250 Stockport Road, Timperley, two Metrolink stops from Altrincham with free parking. Walk in or book a same-day appointment seven days a week and we'll sort vaccinations, antimalarials and any yellow fever certificate in one visit.