📍 250 Stockport Rd, Timperley, Altrincham
Altrincham Travel Clinic

Safari travel health

Travel vaccines for an African safari

Planning a safari? Yellow Fever and malaria are the two big things to get right, alongside a few key vaccines. Here's what UK safari travellers are usually advised — with your personal plan and certificate sorted in one visit.

Yellow Fever & certificate
Malaria tablets
Hepatitis A
Typhoid
Rabies

Overview

What vaccines do I need for an African safari?

A safari is the trip of a lifetime — and the health preparation matters more than for many holidays. Across the classic safari countries of East and Southern Africa, two things stand out: Yellow Fever (which is recommended or required in several countries, and whose certificate is checked when crossing borders) and malaria (a serious risk in most safari areas, where antimalarial tablets are usually essential).

On top of those, a small set of vaccines protects against food, water and animal-related risks. The exact list depends on which countries and parks you're visiting — use the country guides below, then we'll confirm your personal plan at a short consultation.

Plan ahead

Book 4–6 weeks before you fly

Yellow Fever must be given at least 10 days before travel for the certificate to be valid, some vaccines need more than one dose, and malaria tablets may need starting before you go — so safari trips really benefit from planning ahead. Travelling sooner? Come in anyway; there's almost always something we can do.

Yellow Fever

Yellow Fever and the certificate on safari

Some safari countries (such as Uganda and Rwanda) require the Yellow Fever vaccine for entry. Many others (such as South Africa, Botswana, Namibia, Zambia and Zimbabwe) have no yellow fever themselves but require a certificate if you arrive from — or pass through — a risk country, which is extremely common on multi-country safaris. The certificate is valid for life. As a registered Yellow Fever Vaccination Centre, we vaccinate and issue the official certificate in one visit.

  • Required for entry to some countries; required as a certificate from a risk country in others
  • Single dose at least 10 days before travel; certificate valid for life
  • We're a registered Yellow Fever Vaccination Centre
Yellow Fever vaccine & certificate

Malaria & mosquitoes

Malaria is the biggest risk on most safaris

Most classic safari areas — the Masai Mara, Serengeti, South Luangwa, the Okavango, Kruger's lowveld and more — carry a real malaria risk, and antimalarial tablets are usually essential. Risk varies by region and season, and is lower at high altitude (such as the gorilla parks). We'll recommend the right tablets for your exact route and pair them with bite-protection advice.

  • Antimalarial tablets advised for most safari itineraries
  • Use repellent, cover up at dawn and dusk, and sleep under treated nets
  • Seek urgent medical help for any fever during your trip or for up to a year after
Malaria tablets & dosing

FAQ

African safari vaccines — FAQs

It depends on the countries on your itinerary. Some (such as Uganda and Rwanda) require it for entry; many others require a certificate if you arrive from a risk country, which is common on multi-country trips. We'll work out exactly what your route needs and issue the official certificate.

For most safari areas, yes — malaria is a serious risk in places like the Masai Mara, Serengeti, South Luangwa and the Okavango. Risk is lower at high altitude (such as the gorilla parks) and in a few southern areas. We'll recommend the right tablets for your exact route.

Gorilla trekking in Uganda and Rwanda needs Yellow Fever (required for entry), Hepatitis A and Typhoid, with Tetanus/Diphtheria/Polio up to date, plus malaria tablets and usually Rabies. See the Uganda and Rwanda guides for detail.

Beach extensions like Zanzibar, Mombasa or the Mozambique coast are usually still malaria areas and may have their own Yellow Fever certificate checks, so they're included in your plan. We'll cover the whole trip together.

Ideally 4–6 weeks before travel — and at least 10 days before for any Yellow Fever certificate. We can still help at shorter notice.

Medically reviewed by Muhammad Adnan, Superintendent Pharmacist (GPhC reg. 2073652) · Last reviewed 2026-06-03

Planning an African safari?

Book a quick consultation at our Timperley clinic near Manchester and we'll sort your Yellow Fever certificate, vaccinations and malaria tablets for every country on your route.