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Altrincham Travel Clinic

Destination guide

Travel vaccines for Cambodia

From the temples of Angkor to the streets of Phnom Penh and the rural Mekong, here is what UK travellers actually need before a trip to Cambodia, and why bite avoidance often matters more than tablets.

Hepatitis A
Typhoid
Rabies
Japanese encephalitis
Dengue awareness
Sunrise over the temples of Angkor Wat, Cambodia

Cambodia

What vaccinations do I need for Cambodia?

A Cambodia trip usually pairs the temple crowds of Angkor with river towns and, increasingly, the remote north-east. For most visitors the essentials are hepatitis A, typhoid and a tetanus booster, with rabies and Japanese encephalitis worth weighing up for anyone spending time rurally. Cambodia's under-resourced medical system is part of the reasoning — reliable rabies treatment can be hard to reach quickly outside Phnom Penh and Siem Reap.

Rabies and Japanese encephalitis come up in a lot of Cambodia consultations, more so than for some neighbouring countries, because both fit the kind of travel people do here: longer stays, rural and forested areas, cycling between temples, and contact with animals or rice-paddy environments. Malaria, by contrast, is genuinely low risk for most itineraries, and antimalarial tablets are not generally recommended. These notes are general guidance drawn from TravelHealthPro (UKHSA and NaTHNaC), and the right combination for your trip is best confirmed at a short consultation with us.

Plan ahead

Book four to six weeks before you fly

Book four to six weeks out where you can. If rabies is on your list for a rural Cambodia trip, that is three doses over three to four weeks; Japanese encephalitis is two doses about a month apart. Short notice is still worth a visit.

Recommended vaccines

Cambodia vaccine recommendations

These are the vaccines TravelHealthPro lists for Cambodia, split into those most travellers should consider and those that depend on your individual plans. We will confirm exactly which you need at your appointment.

Hepatitis A

Most travellers

Spread through contaminated food and water, hepatitis A is a sensible baseline for Cambodia given the street-food culture and variable sanitation outside the main hotels.

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Tetanus

Most travellers

A cut or graze while temple-climbing or trekking is easy to pick up, so we will check your tetanus cover is current and offer a booster if it has lapsed.

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Typhoid

Most travellers

Typhoid risk follows food and water hygiene, which makes it worth having for the kind of adventurous eating most people do in Cambodian markets and rural towns.

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Chikungunya

Some travellers

Spread by daytime-biting mosquitoes, chikungunya can be discussed for some travellers, particularly older adults or those with longer or repeated rural stays.

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Dengue

Some travellers

Dengue occurs countrywide and the vaccine may be considered for travellers aged four and over who have had a previous confirmed dengue infection, so let us know if that applies to you.

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Hepatitis B

Some travellers

Worth considering for longer trips, healthcare or volunteer work, or any chance of needing medical or dental treatment while you are in Cambodia.

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Japanese encephalitis

Some travellers

Carried by mosquitoes around rice fields and pig farming, this is a common recommendation for stays of a month or more, repeat visits, or rural travel during the May to October peak.

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Measles

Some travellers

We will check you have had two documented doses of MMR, as measles still circulates in the region and protection is especially important for younger travellers.

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Rabies

Some travellers

Often relevant for Cambodia given roaming dogs, cycling between temples and remote areas with limited access to treatment, so pre-exposure doses are frequently worth discussing.

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Tuberculosis

Some travellers

The BCG vaccine is usually only relevant for longer stays or close contact with local communities, typically in younger travellers who have not had it before.

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Entry rules — separate from your jabs

Yellow fever certificate: what Cambodia requires

A yellow fever certificate requirement is a legal condition of entry — it is not the same thing as the vaccine being recommended for your health. The recommendation (when there is one) appears in the vaccine list above; the entry rule is below.

Flying direct from the UK? No yellow fever certificate needed for Cambodia

Cambodia only asks for a certificate (ICVP) from travellers aged 1 year+ who arrive from — or pass through — a country with yellow fever risk, and airport layovers over 12 hours in a risk country count. That catches out multi-country itineraries, so check your whole route, not just your destination.

There is no yellow fever transmission risk in Cambodia itself — this rule exists purely to stop the virus being carried in from elsewhere.

Mosquito-borne illness

Malaria, dengue and bite avoidance in Cambodia

Malaria is low risk across Cambodia and antimalarial tablets are not generally recommended. The risk around Angkor Wat and the temple complexes is very low, and tablets are usually only considered for specific rural or forested border areas, often the provinces bordering Thailand. Dengue, however, is present countrywide and is spread by daytime-biting mosquitoes, so for most travellers good bite avoidance is the single most useful thing you can do: a DEET-based repellent, loose long sleeves at dawn and dusk, and a room that is screened or air-conditioned. Malaria in Cambodia is limited to rural and forested border areas, but resistance to some antimalarial drugs in this region means the choice of tablet matters — we'll advise the right one for your route.

  • Very low malaria risk around Angkor Wat and Siem Reap
  • Tablets generally reserved for rural or forested border areas
  • Dengue is countrywide, so repellent and covering up matter year-round
  • Bring a DEET-based repellent and reapply through the day
Malaria advice and dosing
Close-up of a mosquito on skin

FAQ

Cambodia travel health: common questions

Do I need malaria tablets for Cambodia?
For most itineraries, no. Malaria risk is low across Cambodia and antimalarial tablets are not generally recommended, with very low risk around Angkor Wat and the main tourist areas. Tablets are usually only considered for specific rural or forested border regions. Because dengue is present countrywide, bite avoidance with a good repellent matters more than tablets for the typical traveller. We can review your exact route at a consultation.
Should I have the rabies vaccine for Cambodia?
It is worth discussing for many Cambodia trips. Stray and roaming dogs are common, and people often cycle between temples or travel to remote areas where prompt treatment after a bite can be hard to reach. Pre-exposure rabies vaccination is given as a short course and is most useful for longer stays, rural travel and trips with limited medical access. You can read more on our rabies page at /vaccines/rabies.
Is Japanese encephalitis a real risk for travellers to Cambodia?
It can be. Japanese encephalitis occurs countrywide with a seasonal peak between May and October, and the mosquitoes that carry it breed around rice fields and pig farming. The vaccine is commonly recommended for stays of a month or more, repeat visits, uncertain itineraries, or rural travel during the season. For a short city-based trip it is usually less of a priority, but we will weigh it against your specific plans.
Do I need a yellow fever certificate for Cambodia?
There is no yellow fever in Cambodia itself. However, a yellow fever certificate is required if you are arriving after visiting, or spending twelve hours or more transiting through, a country where yellow fever is a risk. If your trip includes parts of Africa or South America beforehand, bring your travel details to your appointment so we can check whether a certificate applies. We are a registered yellow fever centre and can advise and vaccinate if needed.
What about dengue, and is there a vaccine?
Dengue is present throughout Cambodia and is spread by mosquitoes that bite during the day, so consistent bite avoidance is your main defence. A dengue vaccine exists and may be considered for travellers aged four and over who have had a previous laboratory-confirmed dengue infection. If that describes you, mention it when you book and we can discuss whether it is appropriate.
How far in advance should I book my Cambodia vaccines?
Ideally four to six weeks before you travel, because some vaccines need more than one dose to give full protection. If your trip is sooner than that, please still come in. We can often use an accelerated schedule or prioritise the vaccines that matter most for your itinerary, alongside practical bite-avoidance and travel-kit advice.
Medically reviewed by Muhammad Adnan, Superintendent Pharmacist (GPhC reg. 2073652) · Last reviewed 2026-08-19
Sources:TravelHealthPro — Cambodia·NHS — Travel vaccinations·NHS — MalariaExternal links open in a new tab. Public-health guidance is reproduced under the Open Government Licence where applicable.

Get ready for Cambodia with confidence

Book a short travel-health consultation in Timperley and we will tailor your vaccines to your route, from Angkor Wat to the rural Mekong, and answer any questions about malaria, dengue and staying well on the road.