Travel health alerts
Disease outbreak alerts for South Sudan
4 outbreaks reported for South Sudan
Last checked against TravelHealthPro on 2026-07-26.
cVDPV1
Reported 21 April 2026Spread through contaminated food and water
As of 20 April 2026, two cVDPV1 cases were reported from the Upper Nile region. Onset of paralysis in both cases was February 2026.
There's a vaccine for this
This is a polio strain — make sure your polio booster is up to date; some countries require proof of recent vaccination to leave.
Cholera
Reported 17 February 2026Spread through contaminated food and water
As of 16 February 2026, a total of 98,372 cholera cases, including 1,624 deaths, have been reported in South Sudan since this outbreak began in September 2024. Cases have been reported in 55 counties, across nine states and all three administrative areas.
There's a vaccine for this
Stick to safe water and well-cooked food, wash hands often — an oral vaccine is available for higher-risk trips.
Marburg virus disease
Reported 19 January 2026Spread by close or bodily-fluid contact
As of 12 January 2026, a total of three suspected Marburg virus disease cases have been reported in South Sudan. Two of these suspected cases travelled to Marburg virus disease affected areas in Ethiopia in November 2025 and one suspected case is believed to be possible community spread.
No vaccine — how to stay safe
Risk to ordinary travellers is very low. Avoid sick people, bodily fluids, caves/mines with bats, and bushmeat.
Mpox
Reported 06 August 2025Spread by close or bodily-fluid contact
As of 31 July 2025, a total of 17 mpox clade Ib cases, with no deaths, have been confirmed in South Sudan for 2025.
No vaccine — how to stay safe
Avoid close skin-to-skin contact with anyone who has a rash or lesions, and contact with wild animals; wash hands often.
Travelling to South Sudan?
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Contains public sector information from TravelHealthPro (NaTHNaC), licensed under the Open Government Licence v3.0. © UK Health Security Agency. Open Government Licence v3.0. This page is general guidance, not medical advice — confirm what you need for your trip with our travel health team.