Travel health alerts
Disease outbreak alerts for South Sudan
5 outbreaks reported for South Sudan
Last checked against TravelHealthPro on 2026-09-16.
cVDPV2
Reported 10 September 2026Spread through contaminated food and water
As of 2 September 2026, a total of three of circulating vaccine-derived poliovirus type 2 (cVDPV2) cases were reported from Jonglei and Warrap states in South Sudan. These are the first cVDPV2 cases reported in 2026. Onset of paralysis was reported in May, June and July 2026 respectively.
There's a vaccine for this
This is a polio strain — make sure your polio booster is up to date; some countries require proof of recent vaccination to leave.
Polio
Reported 10 September 2026Spread through contaminated food and water
As of 2 September 2026, a total of three of circulating vaccine-derived poliovirus type 2 (cVDPV2) cases were reported from Jonglei and Warrap states in South Sudan. These are the first cVDPV2 cases reported in 2026. Onset of paralysis was reported in May, June and July 2026 respectively.
There's a vaccine for this
Make sure your polio booster is up to date — some affected countries also require proof of recent vaccination to leave.
Cholera
Reported 30 July 2026Spread through contaminated food and water
As of 26 July 2026, 109,049 cholera cases and 1,716 deaths have been reported across 55 counties in nine states across South Sudan, since the outbreak began in September 2024. This outbreak is the largest in South Sudan since 2011.
There's a vaccine for this
Stick to safe water and well-cooked food, wash hands often — an oral vaccine is available for higher-risk trips.
cVDPV1
Reported 21 April 2026Spread through contaminated food and water
As of 20 April 2026, two cVDPV1 cases were reported from the Upper Nile region. Onset of paralysis in both cases was February 2026.
There's a vaccine for this
This is a polio strain — make sure your polio booster is up to date; some countries require proof of recent vaccination to leave.
Marburg virus disease
Reported 19 January 2026Spread by close or bodily-fluid contact
As of 12 January 2026, a total of three suspected Marburg virus disease cases have been reported in South Sudan. Two of these suspected cases travelled to Marburg virus disease affected areas in Ethiopia in November 2025 and one suspected case is believed to be possible community spread.
No vaccine — how to stay safe
Risk to ordinary travellers is very low. Avoid sick people, bodily fluids, caves/mines with bats, and bushmeat.
Travelling to South Sudan?
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Contains public sector information from TravelHealthPro (NaTHNaC), licensed under the Open Government Licence v3.0. © UK Health Security Agency. Open Government Licence v3.0. This page is general guidance, not medical advice — confirm what you need for your trip with our travel health team.