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Altrincham Travel Clinic

Destination guide

Travel vaccines for South Sudan

South Sudan requires a Yellow Fever certificate from all travellers, usually asked for with the visa and checked on arrival. Malaria risk is high throughout. Here's what's advised — including the certificate we issue.

Yellow Fever required
Certificate for visa
Malaria tablets
Hepatitis A
Typhoid
Aerial view of Juba, the capital of South Sudan

Overview

What vaccinations do I need for South Sudan?

For South Sudan, Yellow Fever vaccination is required from all travellers aged 9 months and over, and the certificate is typically requested for the visa and checked on arrival. Most travellers are also advised Hepatitis A, Typhoid and an up-to-date Tetanus, Diphtheria & Polio booster. Depending on your trip, Hepatitis B, Rabies, Cholera and Meningitis (ACWY) may be added. Malaria risk is high countrywide all year, so antimalarial tablets are recommended for essentially all travellers.

This is a general guide based on UK travel-health advice from TravelHealthPro (NaTHNaC) and NHS Fit for Travel, and most visitors travel for humanitarian, NGO, UN, business or VFR reasons. Your exact list is confirmed at a short consultation in Timperley, near Manchester, where we'll also issue your official Yellow Fever certificate. Please check current FCDO advice before booking.

Plan ahead

Sort Yellow Fever and malaria before you go

Your Yellow Fever certificate is needed for the visa/entry and only becomes valid 10 days after the jab, and malaria tablets may need starting before you travel — so plan early. Aim for 4–6 weeks ahead, and check current FCDO advice for South Sudan. Travelling sooner? Come in anyway and we'll do what we can.

Recommended vaccinations

Vaccines commonly advised for South Sudan

Grouped by how often they're recommended. Your personal list is confirmed at consultation. Vaccine guidance is based on public health information from TravelHealthPro (UKHSA/NaTHNaC) and NHS Fit for Travel.

Yellow Fever (including certificate)

Required

Required from all travellers aged 9 months and over, with transmission risk in all areas. The certificate is typically needed for the visa/entry. We issue the official certificate, valid for life.

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Hepatitis A

Most travellers

Spread through contaminated food and water — advised for nearly all trips.

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Typhoid

Most travellers

Recommended for most travellers given poor sanitation, especially those visiting friends and relatives.

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Tetanus, Diphtheria & Polio

Most travellers

A combined booster is recommended; polio boosters are advised as vaccine-derived polio has been reported in South Sudan.

Learn more

Hepatitis B

Some travellers

Advised where exposure to blood/body fluids is possible — medical care, longer stays — and can be considered for all travellers.

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Rabies

Some travellers

Pre-exposure advised for occupational/activity risk or where prompt post-exposure treatment is limited.

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Cholera

Some travellers

Advised for aid/relief workers and outbreak-affected areas — South Sudan has recurrent cholera outbreaks.

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Meningitis (ACWY)

Some travellers

South Sudan lies in the African meningitis belt — advised for longer stays, backpackers, VFR visitors and healthcare workers.

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Chikungunya

Some travellers

Spread by daytime-biting Aedes mosquitoes; a newer vaccine may suit some travellers alongside strict bite avoidance.

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Dengue

Some travellers

Dengue occurs in South Sudan. The dengue vaccine may be considered for travellers aged 4 and over who have had a previous, laboratory-confirmed dengue infection — bite avoidance remains essential for everyone.

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Measles (MMR)

Some travellers

Make sure you have had two documented doses of MMR, as measles still circulates in many regions.

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Tuberculosis

Some travellers

BCG is usually only relevant for longer stays or close community contact, typically younger travellers who have not had it before.

Learn more

Entry rules — separate from your jabs

Yellow fever certificate: what South Sudan requires

A yellow fever certificate requirement is a legal condition of entry — it is not the same thing as the vaccine being recommended for your health. The recommendation (when there is one) appears in the vaccine list above; the entry rule is below.

South Sudan requires a yellow fever certificate from ALL arrivals

Every traveller aged 9 months or older must show a valid International Certificate of Vaccination or Prophylaxis (ICVP) — or a medical exemption letter — to enter South Sudan, whichever country they arrive from. The certificate becomes valid 10 days after vaccination, so plan ahead.

Separately, yellow fever transmission does occur in South Sudan — so the vaccine itself may be advised for your health; see the vaccine list above and we'll confirm at your consultation.

Yellow Fever & your visa

Yellow Fever certificate for South Sudan

South Sudan requires proof of Yellow Fever vaccination from all travellers aged 9 months and over. The certificate is typically requested for the visa or e-Visa and checked on arrival, so you must carry it. As a registered Yellow Fever Vaccination Centre, we vaccinate you and issue the official ICVP certificate in one visit.

  • Required from all travellers aged 9 months and over
  • Typically needed for the visa and checked at the border — carry your certificate
  • Single dose, valid for life; certificate valid 10 days after vaccination
  • We're a registered Yellow Fever Vaccination Centre and issue the official certificate
Yellow Fever vaccine & certificate
Yellow fever vaccination and certificate for South Sudan

Malaria & mosquitoes

Malaria in South Sudan

Malaria risk is high throughout South Sudan, in all areas, all year, with reported upsurges in recent years. Antimalarial tablets are recommended for essentially all travellers — we'll advise the most suitable option for your trip and supply it on the day.

  • High risk countrywide, all year — tablets advised for all travellers
  • Use repellent, cover up after sunset, and sleep under a treated net
  • Seek urgent medical help for any fever during or after your trip
Malaria tablets & dosing
Mosquito-bite protection for travel to South Sudan

FAQ

South Sudan travel vaccines — FAQs

Medically reviewed by Muhammad Adnan, Superintendent Pharmacist (GPhC reg. 2073652) · Last reviewed 2026-06-17
Sources:TravelHealthPro (NaTHNaC) — South Sudan·NHS Fit for Travel — South Sudan·TravelHealthPro — Yellow Fever factsheetExternal links open in a new tab. Public-health guidance is reproduced under the Open Government Licence where applicable.

Getting ready for South Sudan?

Book a consultation at our Timperley clinic near Manchester and we'll sort your Yellow Fever certificate, vaccinations and malaria tablets — with evening and weekend slots for aid and business travel.

Hero photo: Aerial view of Juba, South Sudan — Umar Sheriff Habibullah, CC BY-SA 4.0, via Wikimedia Commons.