Destination guide
Travel vaccines for South Sudan
South Sudan requires a Yellow Fever certificate from all travellers, usually asked for with the visa and checked on arrival. Malaria risk is high throughout. Here's what's advised — including the certificate we issue.

Overview
What vaccinations do I need for South Sudan?
For South Sudan, Yellow Fever vaccination is required from all travellers aged 9 months and over, and the certificate is typically requested for the visa and checked on arrival. Most travellers are also advised Hepatitis A, Typhoid and an up-to-date Tetanus, Diphtheria & Polio booster. Depending on your trip, Hepatitis B, Rabies, Cholera and Meningitis (ACWY) may be added. Malaria risk is high countrywide all year, so antimalarial tablets are recommended for essentially all travellers.
This is a general guide based on UK travel-health advice from TravelHealthPro (NaTHNaC) and NHS Fit for Travel, and most visitors travel for humanitarian, NGO, UN, business or VFR reasons. Your exact list is confirmed at a short consultation in Timperley, near Manchester, where we'll also issue your official Yellow Fever certificate. Please check current FCDO advice before booking.
Plan ahead
Sort Yellow Fever and malaria before you go
Your Yellow Fever certificate is needed for the visa/entry and only becomes valid 10 days after the jab, and malaria tablets may need starting before you travel — so plan early. Aim for 4–6 weeks ahead, and check current FCDO advice for South Sudan. Travelling sooner? Come in anyway and we'll do what we can.
Recommended vaccinations
Vaccines commonly advised for South Sudan
Grouped by how often they're recommended. Your personal list is confirmed at consultation. Vaccine guidance is based on public health information from TravelHealthPro (UKHSA/NaTHNaC) and NHS Fit for Travel.
Yellow Fever (including certificate)
Required
Required from all travellers aged 9 months and over, with transmission risk in all areas. The certificate is typically needed for the visa/entry. We issue the official certificate, valid for life.
Hepatitis A
Most travellers
Spread through contaminated food and water — advised for nearly all trips.
Typhoid
Most travellers
Recommended for most travellers given poor sanitation, especially those visiting friends and relatives.
Tetanus, Diphtheria & Polio
Most travellers
A combined booster is recommended; polio boosters are advised as vaccine-derived polio has been reported in South Sudan.
Hepatitis B
Some travellers
Advised where exposure to blood/body fluids is possible — medical care, longer stays — and can be considered for all travellers.
Rabies
Some travellers
Pre-exposure advised for occupational/activity risk or where prompt post-exposure treatment is limited.
Cholera
Some travellers
Advised for aid/relief workers and outbreak-affected areas — South Sudan has recurrent cholera outbreaks.
Meningitis (ACWY)
Some travellers
South Sudan lies in the African meningitis belt — advised for longer stays, backpackers, VFR visitors and healthcare workers.
Chikungunya
Some travellers
Spread by daytime-biting Aedes mosquitoes; a newer vaccine may suit some travellers alongside strict bite avoidance.
Dengue
Some travellers
Dengue occurs in South Sudan. The dengue vaccine may be considered for travellers aged 4 and over who have had a previous, laboratory-confirmed dengue infection — bite avoidance remains essential for everyone.
Measles (MMR)
Some travellers
Make sure you have had two documented doses of MMR, as measles still circulates in many regions.
Tuberculosis
Some travellers
BCG is usually only relevant for longer stays or close community contact, typically younger travellers who have not had it before.
Entry rules — separate from your jabs
Yellow fever certificate: what South Sudan requires
A yellow fever certificate requirement is a legal condition of entry — it is not the same thing as the vaccine being recommended for your health. The recommendation (when there is one) appears in the vaccine list above; the entry rule is below.
South Sudan requires a yellow fever certificate from ALL arrivals
Every traveller aged 9 months or older must show a valid International Certificate of Vaccination or Prophylaxis (ICVP) — or a medical exemption letter — to enter South Sudan, whichever country they arrive from. The certificate becomes valid 10 days after vaccination, so plan ahead.
Separately, yellow fever transmission does occur in South Sudan — so the vaccine itself may be advised for your health; see the vaccine list above and we'll confirm at your consultation.
Yellow Fever & your visa
Yellow Fever certificate for South Sudan
South Sudan requires proof of Yellow Fever vaccination from all travellers aged 9 months and over. The certificate is typically requested for the visa or e-Visa and checked on arrival, so you must carry it. As a registered Yellow Fever Vaccination Centre, we vaccinate you and issue the official ICVP certificate in one visit.
- Required from all travellers aged 9 months and over
- Typically needed for the visa and checked at the border — carry your certificate
- Single dose, valid for life; certificate valid 10 days after vaccination
- We're a registered Yellow Fever Vaccination Centre and issue the official certificate

Malaria & mosquitoes
Malaria in South Sudan
Malaria risk is high throughout South Sudan, in all areas, all year, with reported upsurges in recent years. Antimalarial tablets are recommended for essentially all travellers — we'll advise the most suitable option for your trip and supply it on the day.
- High risk countrywide, all year — tablets advised for all travellers
- Use repellent, cover up after sunset, and sleep under a treated net
- Seek urgent medical help for any fever during or after your trip

FAQ
South Sudan travel vaccines — FAQs
Getting ready for South Sudan?
Book a consultation at our Timperley clinic near Manchester and we'll sort your Yellow Fever certificate, vaccinations and malaria tablets — with evening and weekend slots for aid and business travel.
